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Towards Tailored Gut Microbiome-Based and Dietary Interventions for Promoting the Development and Maintenance of a Healthy Brain.

2021

Mental health is determined by a complex interplay between the Neurological Exposome and the Human Genome. Multiple genetic and non-genetic (exposome) factors interact early in life, modulating the risk of developing the most common complex neurodevelopmental disorders (NDDs), with potential long-term consequences on health. To date, the understating of the precise etiology underpinning these neurological alterations, and their clinical management pose a challenge. The crucial role played by diet and gut microbiota in brain development and functioning would indicate that modulating the gut-brain axis may help protect against the onset and progression of mental-health disorders. Some nutriti…

0301 basic medicineExposomePsychological interventionReviewGut floraBioinformaticsdigestive systemPediatricsRJ1-57003 medical and health sciences0302 clinical medicineMedicineHuman viromeMicrobiomeprecision nutritionviromebiologygut microbiotaneurodevelopmentbusiness.industrybiology.organism_classificationmedicine.diseaseMental healthGut microbiomegut bacterial microbiomepsychiatry and mental healthMalnutrition030104 developmental biologyPediatrics Perinatology and Child HealthGut microbiotabusinessdiet030217 neurology & neurosurgeryFrontiers in pediatrics
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